Diagnosis and clinical use of bromperidol in HIV-related psychoses in a sample of seropositive patients with brain damage
| Autor: | A. Scasso, M. D. Santa, A. Nuccorini, P. Perretta, E. Zaccagnini, C Nisita, G.B. Cassano |
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| Rok vydání: | 1992 |
| Předmět: |
medicine.medical_specialty
Chemotherapy Psychosis business.industry medicine.medical_treatment Brain damage medicine.disease Surgery Psychiatry and Mental health Acquired immunodeficiency syndrome (AIDS) Bromperidol Internal medicine Immunopathology medicine Haloperidol Pharmacology (medical) Viral disease medicine.symptom business medicine.drug |
| Zdroj: | International Clinical Psychopharmacology. 7:95-99 |
| ISSN: | 0268-1315 |
| Popis: | We evaluated in an open trial the safety and effectiveness of a high-potency neuroleptic (bromperidol) for the treatment of AIDS-related organic mental syndromes. Eleven (nine men and two women) seropositive patients with psychotic features were included; six were intravenous drug users (IVDU) and five were not IVDU (NON-IVDU). On the basis of the achievement of a CGI score of 1 or 2 (much improved or very much improved) at the fourth week, nine patients were considered responders, one was a partial responder and one was a non-responder. From a clinical point of view, "positive" psychotic symptoms had a significant remission, while the "negative" ones seemed to be less sensitive or insensitive to bromperidol treatment. |
| Databáze: | OpenAIRE |
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