COMPARISON OF DEXMEDETOMIDINE, BUPRENORPHINE AND FENTANYL AS AN ADJUVANT TO BUPIVACAINE DURING SPINAL ANAESTHESIA FOR HEMIARTHROPLASTY

Autor:	Pradeep R, Joby Thomas
Rok vydání:	2016
Předmět:	Bupivacaine lcsh:R5-130.5 business.industry medicine.medical_treatment α2-Adrenoreceptor Agonist Spinal anesthesia Buprenorphine Fentanyl Spinal Anaesthesia Anesthesia Medicine Dexmedetomidine business Adjuvant lcsh:General works medicine.drug
Zdroj:	Journal of Evidence Based Medicine and Healthcare, Vol 3, Iss 82, Pp 4474-4478 (2016)
ISSN:	2349-2570 2349-2562
Popis:	BACKGROUND Opioids such as fentanyl or buprenorphine are being added as adjuvant to local anaesthetic for spinal anaesthesia. Dexmedetomidine, a new α2 agonist is being tried as an adjuvant in the recent times. MATERIALS AND METHODS The patients were randomised into three Groups (n=30 each) by closed envelope technique. Patients in Group 1 received 10 µg fentanyl with 15 mg of 0.5% hyperbaric bupivacaine, Group 2 received 15 mg of 0.5% hyperbaric bupivacaine supplemented with 30 µg of buprenorphine and Group 3 received 15 mg of 0.5% hyperbaric bupivacaine plus 5 µg dexmedetomidine intrathecally. The time to reach maximum sensory and motor level, the regression time of the same, any adverse effects were recorded. Data were analysed using chi-square test or Fisher’s exact test for categorical data and analysis of variance for continuous data. A value of P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f035a696d8d3ada66707a1822468d3 https://doi.org/10.18410/jebmh/2016/950 Zobrazit plný text záznamu