Clinical and pathologic features of fibroadenoma of the mastopathic type
| Autor: | Goi Sakamoto, Kiyoshi Ohnishi, Hajime Kuroda, Yasuo Toyozumi, Shinji Itoyama, Futoshi Akiyama, Jun-ichi Tamaru, Shuji Momose, Ikuya Takeuchi |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Oncology
Adult medicine.medical_specialty Breast Neoplasms Diagnosis Differential Surgical oncology Internal medicine Breast Fibroadenoma Biopsy medicine Carcinoma Humans skin and connective tissue diseases Pathological Ultrasonography medicine.diagnostic_test business.industry Incidence (epidemiology) Biopsy Needle General Medicine Middle Aged medicine.disease Fibroadenoma body regions Carcinoma Ductal Surgery Female Radiology Differential diagnosis business |
| Zdroj: | Surgery today. 36(7) |
| ISSN: | 0941-1291 |
| Popis: | Fibroadenoma with mastopathic change (FAM) is a relatively uncommon subtype of fibroadenoma of the breast, with a high incidence of pathological misdiagnosis. This histological subtype remains poorly understood because of its rarity. Many questions remain unanswered about its clinicopathological importance, especially in the differential diagnosis of breast cancers. Among 218 breast fibroadenomas surgically resected as excisional biopsies at our institute between 1990 and 2004, 19 were pathologically diagnosed as FAM. We reviewed these 19 patients. The ages of the patients ranged from 20 to 51 years (mean 36.8 years). The tumor sizes ranged from 0.8 to 7 cm (mean 2.1 cm). Six of the 19 patients underwent core needle biopsy, resulting in a diagnosis of fibroadenoma in four patients and atypical ductal hyperplasia in two patients. Ultrasonography showed findings suggestive of solid tubular carcinoma in seven patients, fibroadenoma in ten patients, and unspecific malignant tumors in two. They were not specified clinically. Recognition of this distinctive variant of fibroadenoma is important because it resembles intraductal carcinoma and is increasing in incidence. It is crucial to distinguish FAM from intraductal carcinoma in biopsy specimens. Thus, not only pathologists but also clinicians must be able to recognize this type of fibroadenoma, and cooperate closely to establish an accurate diagnosis. |
| Databáze: | OpenAIRE |
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