The association of arachnoid cysts and focal epilepsy: Hospital based case control study
| Autor: | Aleksandar J. Ristić, Nikola Vojvodić, Vladimir Baščarević, Ivan Nikolic, Ivana Berisavac, Dragoslav Sokić, Andrej Ilankovic, Tijana Đukić |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Adolescent 03 medical and health sciences Epilepsy Young Adult 0302 clinical medicine medicine Humans Cyst In patient Ictal 030212 general & internal medicine Aged Retrospective Studies business.industry Case-control study Ictal eeg Electroencephalography General Medicine Hospital based Middle Aged medicine.disease Magnetic Resonance Imaging Arachnoid Cysts Hospitalization Case-Control Studies Etiology Surgery Female Neurology (clinical) Radiology Epilepsies Partial business 030217 neurology & neurosurgery |
| Zdroj: | Clinical neurology and neurosurgery. 159 |
| ISSN: | 1872-6968 |
| Popis: | Objective Arachnoid cysts (ACs) are common findings in brain MRI. Our aim was to examine frequency and distribution of ACs in patients with focal epilepsy, compared to healthy control subjects, and to investigate the association of AC and electro-clinical features of focal epilepsy. Patients and methods We performed a retrospective case-control study, using data from 180 patients that underwent video-EEG monitoring between 2009 and 2012, and of 114 healthy controlled subjects. Analysis of electro-clinical data and structural MRI images was conducted. Results A significantly higher proportion of ACs in the focal epilepsy group (19/180; 10.5%) compared to healthy control subjects (3/114; 2.6%) (p = 0.012) was identified. Significant congruence of semiological features or interictal and ictal EEG with AC localization was identified in only one MRI nonlesional patient with temporal cyst localization. Conclusion ACs are seen more often in patients with focal epilepsy. Explicit association between focal epilepsy and AC is possible but exceptional. More likely, focal epilepsy and AC share a common etiological ancestor but represent distant and distinct entities. |
| Databáze: | OpenAIRE |
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