Fibronectin in Foreign Body-Induced Sarcomas and Preneoplastic Cells
Autor: | Leo T. Furcht, MacDonald Gc, Brand Kg |
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Rok vydání: | 1983 |
Předmět: |
Pathology
medicine.medical_specialty biology Cell Foreign Bodies medicine.disease Fibronectins Phenotype General Biochemistry Genetics and Molecular Biology Fibronectin Mice medicine.anatomical_structure Murine sarcoma Mice Inbred CBA medicine biology.protein Animals Neoplasm Sarcoma Experimental Foreign body Precancerous Conditions Psychological repression |
Zdroj: | Experimental Biology and Medicine. 172:89-92 |
ISSN: | 1535-3699 1535-3702 |
DOI: | 10.3181/00379727-172-41532 |
Popis: | Foreign body (FB)-induced murine sarcoma cells and advanced preneoplastic cells as well as normal fibroblasts produce fibronectin (FN) in primary culture; cells at early preneoplasia do not. Hence, the neoplastic properties of FB-induced sarcomas do not depend on absence of FN. Temporary FN repression during early preneoplasia is associated with certain phenotypic cell characteristics. |
Databáze: | OpenAIRE |
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