Antibiotic consumption in Turkish hospitals; a multi-centre point prevalence study
| Autor: | Nefise Oztoprak, Serpil Erol, Fatma Aybala Altay, Aziz Ogutlu, İbrahim Erayman, Funda Kocak, Gülsüm Kaya, Vedat Turhan, Ayse Batirel, Salih Hosoglu, Bahri Teker, Mustafa Kasim Karahocagil, Ertugrul Guclu, Tuna Demirdal, Hamdi Sözen, Mustafa Yildirim, Oguz Karabay |
|---|---|
| Přispěvatelé: | Guclu, E, Ogutlu, A, Karabay, O, Demirdal, T, Erayman, I, Hosoglu, S, Turhan, V, Erol, S, Oztoprak, N, Batirel, A, Altay, FA, Kaya, G, Karahocagil, M, Sozen, H, Yildirim, M, Kocak, F, Teker, B, Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü, Güçlü, Ertuğrul, Öğütlü, Aziz, Karabay, Oğuz, Yıldırım, Mustafa, MÜ, Eğitim ve Araştırma Hastanesi, Sözen, Hamdi |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Pediatrics medicine.medical_specialty Consumption Turkey medicine.drug_class 030106 microbiology Cephalosporin Antibiotics 03 medical and health sciences Hospital Antibiotic resistance Clavulanic acid Intensive care Ampicillin medicine Prevalence Humans Pharmacology (medical) Pharmacology & Pharmacy Beta-Lactamase Inhibitors Pharmacology business.industry Antibiotic Sulbactam Drug Utilization Hospitals Anti-Bacterial Agents Infectious Diseases Cross-Sectional Studies Oncology Antibiotic Stewardship business medicine.drug |
| Popis: | WOS: 000396680900004 PubMed ID: 27238248 This multi-centre study aimed to determine the antibiotic consumption in Turkish hospitals by point prevalence. Antibiotic consumption of 14 centres was determined using the DDD method. Among hospitalized patients, 44.8% were using antibiotics and the total antibiotic consumption was 674.5 DDD/1000 patient-days (DPD). 189.6 (28%) DPD of the antibiotic consumption was restricted while 484.9 (72%) DPD was unrestricted. Carbapenems (24%) and beta lactam/beta lactamase inhibitors (ampicillin-sulbactam or amoxicillin-clavulanate; 22%) were the most commonly used restricted and unrestricted antibiotics. Antibiotics were most commonly used in intensive care units (1307.7 DPD). Almost half of the hospitalized patients in our hospitals were using at least one antibiotic. Moreover, among these antibiotics, the most commonly used ones were carbapenems, quinolones and cephalosporins, which are known to cause collateral damage. We think that antibiotic resistance, which is seen at considerably high rates in our hospitals, is associated with this level of consumption. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|