Liquid Crystal Gel Reduces Age Spots by Promoting Skin Turnover
| Autor: | Satomi Kato, Teruaki Nagasawa, Ariella Coler-Reilly, Mina Musashi, Yoko Yamaguchi, Yoshiki Kubota |
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| Rok vydání: | 2014 |
| Předmět: |
Aging
skin care Pharmaceutical Science Stimulation Dermatology lcsh:Chemistry age spots Liquid crystal Stratum corneum medicine stratum corneum Chemical Engineering (miscellaneous) liquid crystal Barrier function Skin care Chromatography integumentary system Spots Chemistry medicine.anatomical_structure lcsh:QD1-999 intercellular lipids Mouse skin Surgery skin turnover Epidermal thickening |
| Zdroj: | Cosmetics, Vol 1, Iss 3, Pp 202-210 (2014) Cosmetics Volume 1 Issue 3 Pages 202-210 |
| ISSN: | 2079-9284 |
| Popis: | Studies have shown that liquid crystals structurally resembling the intercellular lipids in the stratum corneum can beneficially affect the skin when applied topically by stimulating the skin’s natural regenerative functions and accelerating epidermal turnover. In the present study, the effects of applying low concentrations of a liquid crystal gel of our own creation were evaluated using epidermal thickening in mouse skin as an assay for effective stimulation of epidermal turnover. A liquid crystal gel was also applied topically to human facial skin, and analysis was conducted using before-and-after photographs of age spots, measurements of L* values that reflect degree of skin pigmentation, single-layer samples of the stratum corneum obtained via tape-stripping, and measurements of trans-epidermal water loss that reflect the status of the skin’s barrier function. The results suggested that cost-effective creams containing as low as 5% liquid crystal gel might be effective and safely sold as skin care products targeting age spots and other problems relating to uneven skin pigmentation. |
| Databáze: | OpenAIRE |
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