Monophasic mesenchymal synovial sarcoma: Its identification by tissue culture
| Autor: | Emilio Álvarez-Fernández, Julio Escalona-Zapata |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Adult
Male Cancer Research Pathology medicine.medical_specialty Adolescent Response to therapy Cell Soft Tissue Neoplasms Diagnosis Differential Tissue culture Epithelial Differentiation medicine Humans Mesenchymoma Child Cells Cultured business.industry Synovial Membrane Mesenchymal stem cell Soft tissue medicine.disease In vitro Synovial sarcoma medicine.anatomical_structure Oncology business |
| Zdroj: | Cancer. 47:628-635 |
| ISSN: | 1097-0142 0008-543X |
| DOI: | 10.1002/1097-0142(19810201)47:3<628::aid-cncr2820470334>3.0.co;2-d |
| Popis: | Tissue cultures from a series of spindle cell soft tissue sarcomas allowed th identification of five cases in which the neoplastic cells grew as polygonal elements, forming plaques in the same way as epithelial tumors. The similarity of this behavior in vitro to that of normal pleura and synovium, and to monophasic malignant pleural mesothelioma, allowed these tumors to be classified as monophasic synovial sarcomas. None of the five tumors showed specific light-optical features, being composed of fusiform cells with a tendency to form slits in two cases. No true epithelial differentiation was found. The topographic distribution and the response to therapy of the neoplasms were also similar to that found in the usual biphasic tumors. |
| Databáze: | OpenAIRE |
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