Portal blood flow and oxygen usage in dogs after hemorrhage
| Autor: | Anthony H. Goodman, Denis F. J. Halmagyi, Miles J. Little, Desmond Varga, Merrilyn Kennedy |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1970 |
| Předmět: |
medicine.medical_specialty
Cardiac Catheterization Partial Pressure Blood Pressure Shock Hemorrhagic Catecholamines Dogs Oxygen Consumption Internal medicine medicine Animals Cardiac Output Sulfobromphthalein Gastrointestinal tract business.industry Direct observation Blood flow Carbon Dioxide Hydrogen-Ion Concentration Mesenteric Arteries Oxygen Indicator dilution Shock (circulatory) Portal blood Cardiology Lactates Surgery medicine.symptom business Splanchnic Blood Flow Velocity Research Article Liver Circulation |
| Popis: | IN 1960 Sapirstein et al.10 concluded that contrary to standard teaching, the splanchnic blood flow is not disproportionately reduced in hemorrhage despite "the teleological attractiveness of such curtailment which has withstood observation to the contrary for more than 30 years." Notwithstanding, in 1964 it was still claimed6 that in shock blood flow to the intestine is reduced more than to other organs and this alleged phenomenon was attributed a prominent role in the mechanism of irreversible shock. A lucid and detailed review of this problem is given by Grayson and Mendell.3 It appears logical to assume that diversity of technics and of species used may account for some of the misunderstanding. Direct observation of mesenteric vessels, collection of outflowing blood, sulfobromphthalein, indicator dilution, bristle flow meter and some other technics were used to measure portal or splanchnic blood flow in rats, rabbits, monkeys, and, most frequently in dogs. Dogs are reputed to have anatomical peculiarities with respect of hepatic veins which are claimed to contract in hemorrhage causing hepatic outflow obstruction. This response was construed as evidence to suggest that shock experiments on dogs may have little relevance to clinical medicine.8 It is generally agreed that oxygen consumption of the gastrointestinal tract di |
| Databáze: | OpenAIRE |
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