Research progress of near-infrared fluorescence immunoassay

Autor: Lin-Huan Wu, Chen Guangquan, Ai-Jin Ma, Chang Xiaohui, Yan-Kun Peng, Jun-Cai Ma, Li Xiaolin, Zhang Jie, Yang Xiangying
Rok vydání: 2019
Předmět:
Zdroj: Micromachines
Micromachines, Vol 10, Iss 6, p 422 (2019)
ISSN: 2455-3492
DOI: 10.17352/2455-3492.000028
Popis: Near-infrared fluorescence immunoassay has been widely studied in the bio analytical field. This review mainly introduces the basic principles of near-infrared spectroscopy and near-infrared detection technology, and summarizes the properties, characteristics and recent improvement of optical properties and signal intensity of three near-infrared fluorescence probes (i.e. organic fluorophores, quantum dots and rare earth compounds). We describe the applications of near-infrared fluorescence technology in immunoassay, and prospect the application potential of lateral flow assay (LFA) based on this probe in the rapid detection of pathogens. Our team intends to establish a new platform which has highly sensitive near-infrared fluorescence probes (NIFPs) combined with portable and simple immunochromatographic test strips (ICTSs) for rapid detection of food borne viruses. This will provide technical support for a rapid detection on the port.
Databáze: OpenAIRE