CT appearances of pleural infection: analysis of the Second Multi-centre Intra-pleural Sepsis Trial (MIST 2) cohort
| Autor: | Rachel Benamore, James M. Franklin, Fergus V. Gleeson, Emma J. Helm, A Talwar, Najib M. Rahman, D. Addala |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Population Pleural thickening 030218 nuclear medicine & medical imaging Cohort Studies Sepsis 03 medical and health sciences 0302 clinical medicine Humans Medicine Radiology Nuclear Medicine and imaging Multi centre education Aged Retrospective Studies Aged 80 and over education.field_of_study business.industry Small airways Pleural infection Retrospective cohort study General Medicine Middle Aged Pleural Diseases respiratory system medicine.disease respiratory tract diseases 030220 oncology & carcinogenesis Cohort Pleura Female Radiology Tomography X-Ray Computed business |
| Zdroj: | Clinical Radiology. 76:436-442 |
| ISSN: | 0009-9260 |
| Popis: | To determine the prevalence of pleural abnormalities and describe the computed tomography (CT) features observed in a well-characterised population of patients with pleural infection.A retrospective study of a subgroup of patients from the Second Multi-centre Intra-pleural Sepsis Trial (MIST 2) trial was carried out. Patients were diagnosed with pleural infection on robust clinical criteria. CT examinations were assessed by three observers independently for the presence of predefined features. Planned subgroup comparisons of patients with and without evidence of parenchymal infection were performed.Eighty-one patients were included. Parietal pleural thickening and enhancement were seen in 98.7% of patients. Visceral pleural changes were observed in most, including several previously undescribed features. Consolidation was observed in 61.7% of patients and there was a significant association of parenchymal consolidation with CT evidence of small airways infection (p0.001) and visceral pleural thickening and enhancement (p0.05). Features of parenchymal infection were absent in one third of patients.This study provides a comprehensive account of the parietal pleural, visceral pleural, and parenchymal changes of pleural infection on CT. Parenchymal infection is absent in a significant proportion of patients with pleural infection, suggesting that a pneumonic process may not be necessary for the development of pleural infection. |
| Databáze: | OpenAIRE |
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