Cryotherapy in the paediatric airway: Indications, success and safety

Autor: Dirk Schramm, Nadine Freitag, Karsten Kötz, Ignacio Iglesias‐Serrano, Mario Culebras‐Amigo, Vladimir Koblizek, Santiago Pérez‐Tarazona, Enrique Cases Viedma, JT Srikanta, Peter Durdik, Kaid Darwiche, Sune Rubak, Patrick Stafler
Přispěvatelé: Institut Català de la Salut, [Schramm D, Freitag N] Department of General Pediatrics, Neonatology and Pediatric Cardiology, Medical Faculty, University Hospital Düsseldorf, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany. [Kötz K] Queen Silvias Children Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden. [Iglesias-Serrano I] Unitat de Pneumologia Pediàtrica i Fibrosi Quística, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Culebras-Amigo M] Servei de Pneumologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Koblizek V] Department of Pneumology, University Hospital Hradec Kralove, Faculty of Medicine in Hradec Kralove, Charles University, Prague, Czechia, Vall d'Hebron Barcelona Hospital Campus
Rok vydání: 2022
Předmět:
Pulmonary and Respiratory Medicine
Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques
Respiratory System::Bronchoscopy [ANALYTICAL
DIAGNOSTIC AND THERAPEUTIC TECHNIQUES
AND EQUIPMENT]
Medizin
Therapeutics::Cryotherapy [ANALYTICAL
DIAGNOSTIC AND THERAPEUTIC TECHNIQUES
AND EQUIPMENT]
cryobiopsy
Bronchi
personas::Grupos de Edad::niño [DENOMINACIONES DE GRUPOS]
Respiratory System::Lung::Bronchi [ANATOMY]
Bronquis
Broncoscòpia
paediatric bronchoscopy
Bronchoscopy
interventional bronchoscopy
diagnóstico::técnicas y procedimientos diagnósticos::técnicas diagnósticas respiratorias::broncoscopia [TÉCNICAS Y EQUIPOS ANALÍTICOS
DIAGNÓSTICOS Y TERAPÉUTICOS]
Humans
Prospective Studies
Child
airway obstruction
foreign body removal
Persons::Age Groups::Child [NAMED GROUPS]
Foreign Bodies
sistema respiratorio::pulmón::bronquios [ANATOMÍA]
Cryotherapy
cryotherapy
Infants
Fred - Ús terapèutic
terapéutica::crioterapia [TÉCNICAS Y EQUIPOS ANALÍTICOS
DIAGNÓSTICOS Y TERAPÉUTICOS]
Zdroj: Scientia
Schramm, D, Freitag, N, Kötz, K, Iglesias-Serrano, I, Culebras-Amigo, M, Koblizek, V, Pérez-Tarazona, S, Cases Viedma, E, Srikanta, J T, Durdik, P, Darwiche, K, Rubak, S & Stafler, P 2022, ' Cryotherapy in the paediatric airway : Indications, success and safety ', Respirology, vol. 27, no. 11, pp. 966-974 . https://doi.org/10.1111/resp.14353
RESPIROLOGY
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
ISSN: 1440-1843
1323-7799
Popis: Airway obstruction; Cryobiopsy; Paediatric bronchoscopy Obstrucción de las vías respiratorias; Criobiopsia; Broncoscopia pediátrica Obstrucció de les vies respiratòries; Criobiòpsia; Broncoscòpia pediàtrica Background and objective Cryotherapy in interventional bronchoscopy is a new treatment modality, which has recently been made available for the paediatric airway. Lack of experience and safety concerns have led to hesitant adaptation. The aim of this study was to assess indications, success rates and complications of airway cryotherapy in children. Methods Bronchoscopists from medical centre performing cryotherapy in patients between 0 and 18 years were invited to participate in a prospective study based on an online questionnaire. Patient and participant data were collected between June 2020 and June 2021. Results A total of 69 cryotherapy procedures were performed in 57 patients a for three main indications: Biopsy (30), restoration of airway patency (23) and foreign body aspiration (16). The overall success rate was 93%, the remaining 7% were performed for foreign body removal and required a switch of technique. Restoration of airway patency was successfully applied in various pathologies, including mucus plugs, bronchial casts and post traumatic stenosis. The diagnostic yield of transbronchial biopsies was 96%. No severe complications were encountered; one pneumothorax following a cryobiopsy required a chest drain for 48 h. No child was admitted to intensive care or died from a procedural complication. Conclusion In this largest paediatric case collection to date, cryotherapy was safe and carried a high success rate. Cryobiopsy compares favourably to the widely used forceps biopsy and could replace it in the future. Paediatric bronchoscopists are encouraged to add cryotherapy to their armamentarium of airway interventions. Open Access funding enabled and organized by Projekt DEAL.
Databáze: OpenAIRE
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