Complete genome sequence of Halomonas sp. R5-57
| Autor: | Adele Kim Williamson, Erik Hjerde, Christian Karlsen, Concetta De Santi, Bjørn Altermark |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Osmolyte 030106 microbiology Ectoine Biology VDP::Matematikk og Naturvitenskap: 400::Basale biofag: 470::Biokjemi: 476 Genome DNA sequencing Polyhydroxyalkanoates Microbiology 03 medical and health sciences chemistry.chemical_compound VDP::Mathematics and natural science: 400::Basic biosciences: 470::Biochemistry: 476 Genetics Secreted enzymes Salt tolerance Extended Genome Report Gene Whole genome sequencing Halomonas VDP::Mathematics and natural science: 400::Chemistry: 440 Growth temperature biology.organism_classification 030104 developmental biology chemistry VDP::Matematikk og Naturvitenskap: 400::Kjemi: 440 Osmoprotectant |
| Zdroj: | Standards in Genomic Sciences |
| Popis: | The marine Arctic isolate Halomonas sp. R5-57 was sequenced as part of a bioprospecting project which aims to discover novel enzymes and organisms from low-temperature environments, with potential uses in biotechnological applications. Phenotypically, Halomonas sp. R5-57 exhibits high salt tolerance over a wide range of temperatures and has extra-cellular hydrolytic activities with several substrates, indicating it secretes enzymes which may function in high salinity conditions. Genome sequencing identified the genes involved in the biosynthesis of the osmoprotectant ectoine, which has applications in food processing and pharmacy, as well as those involved in production of polyhydroxyalkanoates, which can serve as precursors to bioplastics. The percentage identity of these biosynthetic genes from Halomonas sp. R5-57 and current production strains varies between 99 % for some to 69 % for others, thus it is plausible that R5-57 may have a different production capacity to currently used strains, or that in the case of PHAs, the properties of the final product may vary. Here we present the finished genome sequence (LN813019) of Halomonas sp. R5-57 which will facilitate exploitation of this bacterium; either as a whole-cell production host, or by recombinant expression of its individual enzymes. Electronic supplementary material The online version of this article (doi:10.1186/s40793-016-0192-4) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
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