Extracellular polymeric substance‐mediated tolerance of Pseudomonas aeruginosa biofilms to atmospheric pressure nonthermal plasma treatment

Autor: Padrig B. Flynn, Nida Alshraiedeh, Michael M. Tunney, Brendan Gilmore, Thomas P. Thompson, Stephen A. Kelly
Rok vydání: 2020
Předmět:
Zdroj: Alshraiedeh, N H, Kelly, S A, Thompson, T P, Flynn, P B, Tunney, M M & Gilmore, B F 2020, ' Extracellular polymeric substance-mediated tolerance of Pseudomonas aeruginosa biofilms to atmospheric pressure nonthermal plasma treatment ', Plasma Processes and Polymers, vol. 17, no. 12, 2000108 . https://doi.org/10.1002/ppap.202000108
ISSN: 1612-8869
1612-8850
DOI: 10.1002/ppap.202000108
Popis: Pseudomonas aeruginosa is an opportunistic disease-causing bacterium, with a number of strains exhibiting a mucus-forming (mucoid) phenotype during infection, producing biofilms with a surrounding matrix containing alginate. Atmospheric pressure nonthermal plasmas (APNTP) are an emerging, potential approach to control biofilms across a range of medical and industrial applications. In this study, we examine the effect of plasma treatment on P. aeruginosa biofilms from clinical samples of cystic fibrosis patients, exhibiting both mucoid and non-mucoid types. Biofilms of mucoid strains exhibit significantly elevated APNTP tolerance (p
Databáze: OpenAIRE