Managing Hyperkalemia: Stepping Into a New Frontier
| Autor: | Dexter Wimer, Isha Rana, Antony Q Pham, Timothy Nguyen, Jessica Sexton |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Hyperkalemia Polymers Potassium medicine.medical_treatment Urology chemistry.chemical_element 030204 cardiovascular system & hematology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine Animals Humans Pharmacology (medical) In patient 030212 general & internal medicine Sodium zirconium cyclosilicate Randomized Controlled Trials as Topic business.industry Silicates Disease Management Patiromer Water-Electrolyte Balance medicine.disease Endocrinology chemistry Hemodialysis medicine.symptom Sodium Polystyrene Sulfonate business Kidney disease |
| Zdroj: | Journal of Pharmacy Practice. 30:557-561 |
| ISSN: | 1531-1937 0897-1900 |
| Popis: | Maintaining potassium balance in the body is essential for cellular function. Even a slight increase in normal serum potassium levels (3.5-5.0 mEq/L) can interfere with metabolism, electrical action potentials, and cellular processes. Hyperkalemia is commonly seen in patients with chronic kidney disease (CKD) and in patients on renin–angiotensin–aldosterone system (RAAS) inhibitors. Sodium polystyrene sulfonate (SPS), diuretics, and hemodialysis are currently available methods for removing potassium from the body; however, these options have their limitations. Patiromer (Veltassa) and sodium zirconium cyclosilicate are 2 new therapeutic options that can potentially lead a new frontier in the management of hyperkalemia. This article will review these novel treatments. |
| Databáze: | OpenAIRE |
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