Detecting Pleiotropy and Epistasis Using Variance Components Linkage Analysis in jPAP
| Autor: | Alun Thomas, Sandra J. Hasstedt |
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| Rok vydání: | 2011 |
| Předmět: |
Paper
Analysis of Variance Internet Multivariate statistics Models Genetic Genetic Linkage Inference Epistasis Genetic Genetic Pleiotropy Quantitative trait locus Genetic architecture Pedigree Quantitative Trait Heritable Pleiotropy Genetic linkage Evolutionary biology Genetics Humans Epistasis Software Genetics (clinical) Mathematics |
| Zdroj: | Human Heredity. 72:258-263 |
| ISSN: | 1423-0062 0001-5652 |
| DOI: | 10.1159/000331690 |
| Popis: | jPAP (Java Pedigree Analysis Package) performs variance components linkage analysis of either quantitative or discrete traits. Multivariate linkage analysis of two or more traits (all quantitative, all discrete, or any combination) allows the inference of pleiotropy between the traits. The inclusion of multiple quantitative trait loci in linkage analysis allows the inference of epistasis between loci. A user-friendly graphical user interface facilitates the usage of jPAP. |
| Databáze: | OpenAIRE |
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