Combination of the neutrophil to lymphocyte ratio and the platelet to lymphocyte ratio as a useful predictor for recurrence following radiofrequency ablation of hepatocellular carcinoma
| Autor: | Yong‑Jie Xin, Si‑Rui Fu, Mei‑Xiao Zhan, Bao‑Shan Hu, Li-Gong Lu, Yong Li, Xu He, Kai Chen |
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| Rok vydání: | 2017 |
| Předmět: |
Oncology
Cancer Research medicine.medical_specialty Cirrhosis Lymphocyte Biology Gastroenterology 03 medical and health sciences 0302 clinical medicine Internal medicine medicine Neutrophil to lymphocyte ratio neutrophil to lymphocyte ratio Oncogene platelet to lymphocyte ratio Cancer Articles hepatocellular carcinoma medicine.disease Molecular medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Hepatocellular carcinoma Absolute neutrophil count 030211 gastroenterology & hepatology prognosis |
| Zdroj: | Oncology Letters |
| ISSN: | 1792-1082 1792-1074 |
| DOI: | 10.3892/ol.2017.7291 |
| Popis: | The aim of the present study was to investigate the prognostic potential of a novel inflammation-based system, the combination of the neutrophil to lymphocyte ratio (NLR) and the platelet to lymphocyte ratio (PLR) (CNP), for predicting the survival time of patients with hepatocellular carcinoma (HCC) who had received radiofrequency ablation (RFA). A total of 287 HCC patients treated with RFA were enrolled in the study. Patients with an elevated NLR (>2.58) and an elevated PLR (>131.78) were allocated a score of 2, and patients exhibiting one or neither of these characteristics were allocated a score of 1 or 0, respectively. The association between the CNP and various HCC clinicopathological factors, patterns of recurrence and prognoses were analyzed. The CNP was associated with liver cirrhosis (P=0.015), Child-Pugh class (P=0.024), total bilirubin level (P=0.028), neutrophil count (P |
| Databáze: | OpenAIRE |
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