In vitro activity of telithromycin (HMR 3647) and seven other antimicrobial agents against anaerobic bacteria
Autor: | Grit Ackermann, Reiner Schaumann, M. C. Claros, Arne C. Rodloff, Baerbel Pless |
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Rok vydání: | 2000 |
Předmět: |
Pharmacology
Microbiology (medical) Ketolides biology Telithromycin food and beverages Microbial Sensitivity Tests biology.organism_classification Peptostreptococcus Anti-Bacterial Agents Microbiology Bacteria Anaerobic Infectious Diseases Fusobacterium polycyclic compounds Prevotella medicine bacteria Pharmacology (medical) Macrolides Anaerobic bacteria Bacteroides fragilis Bacteroides thetaiotaomicron Antibacterial agent medicine.drug |
Zdroj: | Journal of Antimicrobial Chemotherapy. 46:115-119 |
ISSN: | 1460-2091 |
DOI: | 10.1093/jac/46.1.115 |
Popis: | We assessed the in vitro activity of telithromycin (HMR 3647) and seven other antimicrobials against 292 strains of obligately anaerobic bacteria. MICs were determined with the microdilution technique and Wilkins-Chalgren broth according to DIN 58940-83. MIC50/MIC90s (mg/L) for telithromycin were 4/4 for Bacteroides fragilis, Bacteroides ovatus and Bacteroides thetaiotaomicron, 2/4 for Fusobacterium spp. and Bilophila wadsworthia, 2/2 for Bacteroides caccae, 1/4 for Bacteroides vulgatus, 0.25/4 for Prevotella spp., > or =0.03/0.5 for Clostridium spp. and 0.125/4 for Peptostreptococcus spp. |
Databáze: | OpenAIRE |
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