Effects of Normovolemic Hemodilution on Survival of Skin Flaps: An Experimental Study
| Autor: | Canser Yilmaz Demir |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Male
0301 basic medicine Necrosis Blood transfusion Survival Adult male medicine.medical_treatment Plasma Substitutes Blood volume Statistics Nonparametric Surgical Flaps 03 medical and health sciences medicine Animals Flap survival Blood Transfusion Hematocrit levels Rats Wistar Skin Hemodilution business.industry Animal Study General Medicine 030104 developmental biology Hematocrit Anesthesia Flap necrosis medicine.symptom Volume loss business |
| Zdroj: | Medical Science Monitor : International Medical Journal of Experimental and Clinical Research |
| ISSN: | 1643-3750 |
| Popis: | BACKGROUND The aim of this study was to investigate the effects of various ratios of hemodilution on the survival of McFarlane's skin flaps. MATERIAL AND METHODS An experimental study was performed on 42 adult male Wistar rats (weighing 260 to 305 g) allocated to a control group without any volume loss and to 6 study groups with hemodilution ratios of 5%, 10%, 15%, 20%, 25%, and 30%. In all subjects, random-pattern McFarlane's skin flaps were uniformly elevated and re-sutured to the donor sites. The amount of necrosis was evaluated on the 7th day postoperatively and compared among the groups. RESULTS The amounts of flap necrosis in the groups with 5%, 10%, 15%, and 20% hemodilution ratios were significantly lower than that of the control group (p |
| Databáze: | OpenAIRE |
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