Antimicrobial properties of a novel copper-based composite coating with potential for use in healthcare facilities

Autor: Rosa Vera, David A. Montero, Marcela Cifuentes, Mirka Pardo, Roberto Vidal, Marisol Gomez, C. Arellano, Ricardo Gálvez, María Angélica Berasaín, Claudio Ramirez
Rok vydání: 2018
Předmět:
0301 basic medicine
Microbiology (medical)
Antimicrobial copper
030106 microbiology
chemistry.chemical_element
Pilot Projects
Drug resistance
Healthcare-associated infections
medicine.disease_cause
lcsh:Infectious and parasitic diseases
Microbiology
03 medical and health sciences
0302 clinical medicine
Listeria monocytogenes
medicine
Infection control
Humans
lcsh:RC109-216
Pharmacology (medical)
030212 general & internal medicine
Equipment and Supplies
Hospital
Antimicrobial properties of copper
Cross Infection
Infection Control
Bacteria
business.industry
Pseudomonas aeruginosa
Research
Public Health
Environmental and Occupational Health
Copper-based composite
Antimicrobial
Copper
Infectious Diseases
chemistry
Staphylococcus aureus
Self-sanitizing coating
Equipment Contamination
business
High-touch surfaces
Disinfectants
Zdroj: Antimicrobial Resistance and Infection Control
Antimicrobial Resistance and Infection Control, Vol 8, Iss 1, Pp 1-10 (2019)
ISSN: 2047-2994
Popis: Background Healthcare-associated infections (HAIs) have a major impact on public health worldwide. Particularly, hospital surfaces contaminated with bacterial pathogens are often the origin of both sporadic cases and outbreaks of HAIs. It has been demonstrated that copper surfaces reduce the microbial burden of high touch surfaces in the hospital environment. Here we report the antimicrobial characterization of a novel composite coating with embedded copper particles, named Copper Armour™. Methods The Copper Armour™ bactericidal activity was evaluated in in vitro assays against several bacterial pathogens, including Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli O157:H7 and Listeria monocytogenes. Additionally, its antimicrobial properties were also evaluated in a pilot study over a nine-week period at an adult intensive care unit. For this, four high touch surfaces, including bed rails, overbed table, bedside table and IV Pole, were coated with Cooper Armour™, and its microbial burden was determined over a nine-week period. Results Copper Armour™ coated samples showed an in vitro reduction in bacterial burden of > 99.9% compared to control samples. Moreover, pilot study results indicate that Copper Armour™ significantly reduces the level of microbial contamination on high-touch surfaces in the hospital environment, as compared with standard surfaces. Conclusions Based on its antimicrobial properties, Copper Armour™ is a novel self-sanitizing coating that exhibits bactericidal activity against important human pathogens and significantly reduces the microbial burden of hospital surfaces. This composite could be used as a self-sanitizing coating to complement infection control strategies in healthcare facilities.
Databáze: OpenAIRE
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