Sero epidemiology ofBordetella pertussis immune responses in a healthy population in northern Greece
| Autor: | Danai Sofianou, Urania Dafni, S. Pournaras, E. Christeli, A. Polyzou, S. Patrinos, Athanassios Tsakris |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Adult
Microbiology (medical) Pediatrics medicine.medical_specialty Bordetella pertussis Adolescent Whooping Cough Clinical Biochemistry Population Filamentous haemagglutinin adhesin Booster dose Pertussis toxin Age Distribution Seroepidemiologic Studies medicine Humans Immunology and Allergy Virulence Factors Bordetella Adhesins Bacterial Child education Whooping cough Aged Retrospective Studies Aged 80 and over Antigens Bacterial education.field_of_study Greece biology Biochemistry (medical) Infant Newborn Public Health Environmental and Occupational Health Infant Original Articles Hematology Middle Aged medicine.disease biology.organism_classification Antibodies Bacterial Medical Laboratory Technology Hemagglutinins Pertussis Toxin Immunization Child Preschool Immunoglobulin G Immunology biology.protein Antibody |
| Zdroj: | Journal of Clinical Laboratory Analysis. 18:211-214 |
| ISSN: | 1098-2825 0887-8013 |
| DOI: | 10.1002/jcla.20025 |
| Popis: | A seroepidemiological study was conducted on a representative sample of the northern Greek population (healthy individuals, age range=1 day to 80 years) to assess the prevalence of antibodies to pertussis toxin (PT) and filamentous hemagglutinin (FHA). Antibody concentrations were significantly elevated with age (analysis of variance (ANOVA), P50 years old compared to children aged 5–10 years (post‐hoc Scheffe analysis, P=0.007). These data suggest that pertussis occurs frequently in Greek adults, and that sometimes a fifth booster vaccine dose is not given after the second year of life. Routine revaccination with the acellular vaccine for children >4 years of age, adolescents, and adults should be considered in order to ensure effective protection of the whole population. J. Clin. Lab. Anal. 18:211–214, 2004. © 2004 Wiley‐Liss, Inc. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|