Increase in brain and pituitary radioimmunoassayable gonadotropin releasing hormone (GnRH) in the European silver eel treated with sexual steroid or human chorionic gonadotropin
| Autor: | Y.A. Fontaine, S. Dufour, B. Kerdelhue |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
endocrine system
Pituitary gland medicine.medical_specialty animal structures Radioimmunoassay Gonadotropin-releasing hormone Peptide hormone Chorionic Gonadotropin Human chorionic gonadotropin Cellular and Molecular Neuroscience Endocrinology Internal medicine medicine Animals Humans Gonadal Steroid Hormones Brain Chemistry Eels Estradiol biology Endocrine and Autonomic Systems Cerebrum Pituitary Hormone-Releasing Hormones General Medicine Silver eel biology.organism_classification medicine.anatomical_structure Neurology Pituitary Gland Female hormones hormone substitutes and hormone antagonists |
| Zdroj: | Neuropeptides. 6:495-502 |
| ISSN: | 0143-4179 |
| DOI: | 10.1016/0143-4179(85)90111-8 |
| Popis: | In the female silver eel, a single estradiol 17 beta (E2) injection significantly increased radioimmunoassayable GnRH (IRGnRH) in the di- and mesencephalon and also in the telencephalon and olfactory lobes, during the first following days; after a chronic estradiol treatment, the pituitary IRGnRH was doubled. In the male silver eel, a single injection of human chorionic gonadotropin (hCG), which is able to induce a progressive testicular development and a durable increase in androgens production, produced a long-term effect on IRGnRH: IRGnRH was significantly increased in the same brain areas as in E2-treated females; a more important rise (10-fold) was observed for pituitary IRGnRH, probably reflecting the accumulation of GnRH in the axonal endings which directly innervate the pituitary in teleosts. These results suggest a positive effect of sexual steroids on GnRH synthesis but not release in the silver eel. |
| Databáze: | OpenAIRE |
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