Clostridium difficile colitis: CT findings and differential diagnosis
Autor: | Gianluca Frezzetti, Silvia Pradella, Vittorio Miele, Ginevra Danti, Sara Guerri, Edvige Lucarelli |
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Rok vydání: | 2019 |
Předmět: |
medicine.medical_specialty
Colon Radiation Colitis Contrast Media Graft vs Host Disease Infectious Colitis Gastroenterology Ischemic colitis 030218 nuclear medicine & medical imaging Diagnosis Differential Clostridium Difficile Colitis 03 medical and health sciences 0302 clinical medicine Ischemia Internal medicine Humans Medicine Radiology Nuclear Medicine and imaging Colitis Radiation Injuries Enterocolitis Pseudomembranous medicine.diagnostic_test Clostridioides difficile business.industry Stool test General Medicine Clostridium difficile medicine.disease Typhlitis Diarrhea 030220 oncology & carcinogenesis medicine.symptom Tomography X-Ray Computed business |
Zdroj: | La radiologia medica. 124:1185-1198 |
ISSN: | 1826-6983 0033-8362 |
Popis: | Clostridium difficile infection (CDI) is a severe and potentially deadly infectious colitis whose incidence is dramatically increasing in the last decades, with more virulent strains. CDI should be suspected in case of unexplained diarrhea and abdominal pain in patients with a recent history of antibiotic use and healthcare exposures; diagnosis is based on a combination of clinical and laboratory findings with demonstration of C. difficile toxins by stool test. The advantages of contrast-enhanced computed tomography (CECT) are the noninvasiveness and the ability to evaluate both the colonic wall and the adjacent soft tissues. Considerable overlap exists between the CECT findings of CDI and those of colitis of other origins, such as typhlitis, ischemic colitis, graft-versus-host disease, radiation colitis and inflammatory bowel diseases; however, some features may help distinguish between these conditions. This paper provides a comprehensive overview of the imaging features of Clostridium difficile colitis and its mimics, with a view to assist the radiologist in reaching the correct diagnosis. |
Databáze: | OpenAIRE |
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