Long term renal function following selective angioembolization for iatrogenic vascular lesions after partial nephrectomy: A matched case-control study
| Autor: | Joshua Aizen, Logan Galansky, O. Ahmed, Ciro Andolfi, Arieh L. Shalhav, Nassib Abou Heidar, Ragheed Saoud |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Urology medicine.medical_treatment Iatrogenic Disease kidney function tests 030232 urology & nephrology Renal function embolization Postoperative Hemorrhage Kidney postoperative period Nephrotoxicity 03 medical and health sciences 0302 clinical medicine Risk Factors nephrectomy Humans Medicine Renal Insufficiency Embolization Aged Proportional Hazards Models business.industry Significant difference Confounding Case-control study Middle Aged Embolization Therapeutic Kidney Neoplasms Diseases of the genitourinary system. Urology Nephrectomy Logistic Models medicine.anatomical_structure Case-Control Studies 030220 oncology & carcinogenesis Female RC870-923 business Follow-Up Studies Glomerular Filtration Rate |
| Zdroj: | Investigative and Clinical Urology, Vol 62, Iss 3, Pp 267-273 (2021) |
| ISSN: | 2466-054X 2466-0493 |
| DOI: | 10.4111/icu.20200510 |
| Popis: | Purpose: Partial nephrectomy is associated with a 1%–2% risk of renal iatrogenic vascular lesion (IVL) that are commonly treated with selective angioembolization (SAE). The theoretical advantage of SAE is preservation of renal parenchyma by targeting only the bleeding portion of the kidney. Our study aims to assess the long-term effect of SAE on renal function, especially that this intervention requires potentially nephrotoxic contrast load injection. Materials and Methods: A retrospective review of patients undergoing partial nephrectomy between 2002 and 2018 was performed, and patients who developed IVL were identified. A 1:4 matched case-control analysis was performed. Paired t-test and χ2 test were used for continuous and categorical variables, respectively. Multivariable logistic and Cox proportional hazards regression analyses were used to identify risk factors and confounders for SAE and postoperative renal function. Results: Eighteen patients found to have an IVL after partial nephrectomy were matched with 72 control patients. IVL's were more common in patients after minimally invasive partial nephrectomy (89% vs. 70%, p=0.008) and in those with higher RENAL nephrometry scores (8.8±2.0 vs. 6.5±1.8, p |
| Databáze: | OpenAIRE |
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