Simplicity and complexity in the cyanobacterial circadian clock mechanism
| Autor: | Yong Ick Kim, Susan S. Golden, Guogang Dong |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Synechococcus
Circadian Rhythm Signaling Peptides and Proteins Mechanism (biology) Gene Expression Profiling Circadian clock macromolecular substances Biology Article Bacterial circadian rhythms Circadian Rhythm Cell biology Gene expression profiling Bacterial Proteins Genetics KaiA Transcriptional regulation Humans bacteria Circadian rhythm Signal transduction Developmental Biology |
| Zdroj: | Current Opinion in Genetics & Development. 20:619-625 |
| ISSN: | 0959-437X |
| Popis: | The circadian clock of the cyanobacterium Synechococcus elongatus PCC 7942 is built on a three-protein central oscillator that can be reconstituted in vitro, a redox-sensitive input for synchronization with the environment, and a bacterial two-component signal transduction pathway for global transcriptional regulation. This review covers the most recent progress in our understanding of the biological and biochemical mechanism of this bacterial clock, such as the discovery of a quinone-binding activity of the oscillator protein KaiA, the molecular mechanism of circadian control of cell division, and the global control of gene expression via modulation of DNA topology. |
| Databáze: | OpenAIRE |
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