Collagen cross linking: Current perspectives

Autor: Srinivas K Rao
Rok vydání: 2013
Předmět:
Collagen cross linking
genetic structures
Epidemiology
molecular mechanisms
Disease
genetic heterogeneity
ectasia
Cornea
Corneal cross-linking techniques
lcsh:Ophthalmology
Early adulthood
crosslinking
new technologies
Photosensitizing Agents
placido disc based topography
piggy back contact lenses
imaging
Treatment options
genetics and genomics
Cross-Linking Reagents
Ectatic disease
medicine.anatomical_structure
Collagen
scleral lens
linkage mapping
medicine.medical_specialty
Keratoconus
whole exome-genome sequencing
Ultraviolet Rays
Disease pathogenesis
Corneal Stroma
keratoconus
prevalence
rigid gas permeable
Vision Disorders
Deregulation
proteomics
Symposium: Keratoconus
medicine
Humans
vernal keratoconjunctivitis
riboflavin
Intensive care medicine
scheimpflug imaging
toric soft contact lens
genome-wide association study
optical coherence tomography
business.industry
Disease progression
Corneal Transplant
Contact lens
medicine.disease
Elasticity
signaling pathways
eye diseases
Surgery
Ophthalmology
SynergEyes
Photochemotherapy
lcsh:RE1-994
modulus
ocular allergy
gene expression
mass spectroscopy
Corneal topography
sense organs
business
genomic loci
Zdroj: Indian Journal of Ophthalmology, Vol 61, Iss 8, Pp 420-421 (2013)
Indian Journal of Ophthalmology
ISSN: 0301-4738
DOI: 10.4103/0301-4738.116071
Popis: Keratoconus is a common ectatic disorder occurring in more than 1 in 1,000 individuals. The condition typically starts in adolescence and early adulthood. It is a disease with an uncertain cause and its progression is unpredictable, but in extreme cases, vision deteriorates and can require corneal transplant surgery. Corneal collagen cross-linking (CCL) with riboflavin (C3R) is a recent treatment option that can enhance the rigidity of the cornea and prevent disease progression. Since its inception, the procedure has evolved with newer instrumentation, surgical techniques, and is also now performed for expanded indications other than keratoconus. With increasing experience, newer guidelines regarding optimization of patient selection, the spectrum of complications and their management, and combination procedures are being described. This article in conjunction with the others in this issue, will try and explore the uses of collagen cross-linking (CXL) in its current form.
Databáze: OpenAIRE