Collagen cross linking: Current perspectives
Autor: | Srinivas K Rao |
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Rok vydání: | 2013 |
Předmět: |
Collagen cross linking
genetic structures Epidemiology molecular mechanisms Disease genetic heterogeneity ectasia Cornea Corneal cross-linking techniques lcsh:Ophthalmology Early adulthood crosslinking new technologies Photosensitizing Agents placido disc based topography piggy back contact lenses imaging Treatment options genetics and genomics Cross-Linking Reagents Ectatic disease medicine.anatomical_structure Collagen scleral lens linkage mapping medicine.medical_specialty Keratoconus whole exome-genome sequencing Ultraviolet Rays Disease pathogenesis Corneal Stroma keratoconus prevalence rigid gas permeable Vision Disorders Deregulation proteomics Symposium: Keratoconus medicine Humans vernal keratoconjunctivitis riboflavin Intensive care medicine scheimpflug imaging toric soft contact lens genome-wide association study optical coherence tomography business.industry Disease progression Corneal Transplant Contact lens medicine.disease Elasticity signaling pathways eye diseases Surgery Ophthalmology SynergEyes Photochemotherapy lcsh:RE1-994 modulus ocular allergy gene expression mass spectroscopy Corneal topography sense organs business genomic loci |
Zdroj: | Indian Journal of Ophthalmology, Vol 61, Iss 8, Pp 420-421 (2013) Indian Journal of Ophthalmology |
ISSN: | 0301-4738 |
DOI: | 10.4103/0301-4738.116071 |
Popis: | Keratoconus is a common ectatic disorder occurring in more than 1 in 1,000 individuals. The condition typically starts in adolescence and early adulthood. It is a disease with an uncertain cause and its progression is unpredictable, but in extreme cases, vision deteriorates and can require corneal transplant surgery. Corneal collagen cross-linking (CCL) with riboflavin (C3R) is a recent treatment option that can enhance the rigidity of the cornea and prevent disease progression. Since its inception, the procedure has evolved with newer instrumentation, surgical techniques, and is also now performed for expanded indications other than keratoconus. With increasing experience, newer guidelines regarding optimization of patient selection, the spectrum of complications and their management, and combination procedures are being described. This article in conjunction with the others in this issue, will try and explore the uses of collagen cross-linking (CXL) in its current form. |
Databáze: | OpenAIRE |
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