Phosphatidylglycerol is implicated in divisome formation and metabolic processes of cyanobacteria
| Autor: | Shigeru Itoh, László Szilák, Bettina Ughy, Tímea O. Kóbori, Ildikó Domonkos, Mihály Kis, Saravanan G. Kuppusamy, Josef Komenda, Tatsuya Uzumaki, Jason Dean, Vendula Krynická, Tomas Zakar, Zoltán Gombos, László Kovács |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Cyanobacteria Physiology Phospholipid Plant Science Photosynthesis Electron Transport 03 medical and health sciences chemistry.chemical_compound FtsZ Synechococcus Phosphatidylglycerol Photosystem I Protein Complex biology technology industry and agriculture Phosphatidylglycerols Metabolism biology.organism_classification 030104 developmental biology Biochemistry chemistry biology.protein lipids (amino acids peptides and proteins) Agronomy and Crop Science Cell Division Bacteria |
| Zdroj: | Journal of Plant Physiology. 223:96-104 |
| ISSN: | 0176-1617 |
| Popis: | Phosphatidylglycerol is an essential phospholipid for photosynthesis and other cellular processes. We investigated the role of phosphatidylglycerol in cell division and metabolism in a phophatidylglycerol-auxotrophic strain of Synechococcus PCC7942. Here we show that phosphatidylglycerol is essential for the photosynthetic electron transfer and for the oligomerisation of the photosynthetic complexes, notably, we revealed that this lipid is important for non-linear electron transport. Furthermore, we demonstrate that phosphatidylglycerol starvation elevated the expressions of proteins of nitrogen and carbon metabolism. Moreover, we show that phosphatidylglycerol-deficient cells changed the morphology, became elongated, the FtsZ ring did not assemble correctly, and subsequently the division was hindered. However, supplementation with phosphatidylglycerol restored the ring-like structure at the mid-cell region and the normal cell size, demonstrating the phosphatidylglycerol is needed for normal septum formation. Taken together, central roles of phosphatidylglycerol were revealed; it is implicated in the photosynthetic activity, the metabolism and the fission of bacteria. |
| Databáze: | OpenAIRE |
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