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Background and Setting: Unicystic ameloblastoma is a unique variant of ameloblastomas that are commonly seen in younger populations. They show a slow growth rate and yet exhibit a relatively local aggression; with the predominant site of origin being the posterior portion of the mandible. Recurrence, following surgical management, is common, depending on the site of involvement, the histological type and the primary method of treatment range from en-bloc excision to curettage. The case presented here is a 16-year-old female patient, who reported to the Department of Oral and Maxillofacial Surgery, with a unilocular radiolucency involving 48 region that was discovered during a routine radiographic examination. The radiolucency measured around 2 x 2 centimetres in size and surrounded the unerupted crown of 48. The lesion was asymptomatic, and a provisional diagnosis of the dentigerous cyst was made. Enucleation of the cyst was done after extraction of 48 under local anaesthesia. On histological examination, the lesional tissue showed cystic areas lined by ameloblastic epithelium and a thin overlying layer of stellate reticulum like cells. The cystic lumen showed large nodular masses of plexiform ameloblastoma confined to the lumen, and an infiltration of ameloblastic epithelium into the connective tissue wall. A confirmatory histopathological diagnosis of unicystic ameloblastoma–mural variant of plexiform type was made. The patient was under observation for 6 months, and there has been no reported recurrence of the lesion. INTRODUCTION Ackerman has described 3 histopathologic variants of unicystic ameloblastoma: 2 1. In the luminal unicystic ameloblastoma: the tumor is located on the luminal surface of the cyst; the lesion also consists of fibrous cyst... |
