Meta-analysis of the diagnostic performance of stress perfusion cardiovascular magnetic resonance for detection of coronary artery disease

Autor: Javed Ehtisham, Michèle Hamon, Guillaume Née, Martial Hamon, Georges Fau, Rémy Morello
Přispěvatelé: BMC, Ed., Service de Radiologie [CHU Caen], Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN), Sérine protéases et physiopathologie de l'unité neurovasculaire, Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Equipe Image - Laboratoire GREYC - UMR6072, Groupe de Recherche en Informatique, Image et Instrumentation de Caen (GREYC), Normandie Université (NU)-Normandie Université (NU)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS), Service de cardiologie et de pathologie vasculaire [CHU Caen], Unité de Biostatistique et de Recherche Clinique (UBRC), Epidémiologie des maladies chroniques : impact des interactions gène environnement sur la santé des populations, Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Droit et Santé, Centre National de la Recherche Scientifique (CNRS)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)-Normandie Université (NU)-Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Centre National de la Recherche Scientifique (CNRS)-École Nationale Supérieure d'Ingénieurs de Caen (ENSICAEN), Normandie Université (NU)
Rok vydání: 2009
Předmět:
Male
lcsh:Diseases of the circulatory (Cardiovascular) system
Adenosine
[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/Imaging
030204 cardiovascular system & hematology
Coronary Angiography
Severity of Illness Index
030218 nuclear medicine & medical imaging
MESH: Magnetic Resonance Imaging
Coronary artery disease
0302 clinical medicine
MESH: Aged
80 and over
Medicine(all)
MESH: Aged
MESH: Myocardial Perfusion Imaging
Aged
80 and over
MESH: Middle Aged
Radiological and Ultrasound Technology
medicine.diagnostic_test
Myocardial Perfusion Imaging
Dipyridamole
Middle Aged
Magnetic Resonance Imaging
MESH: Predictive Value of Tests
3. Good health
[SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
medicine.anatomical_structure
Right coronary artery
Cardiology
Female
Cardiology and Cardiovascular Medicine
Perfusion
medicine.drug
medicine.medical_specialty
MESH: Coronary Circulation
[INFO] Computer Science [cs]
Sensitivity and Specificity
03 medical and health sciences
Myocardial perfusion imaging
Coronary circulation
MESH: Coronary Stenosis
[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system
Predictive Value of Tests
medicine.artery
Internal medicine
MESH: Severity of Illness Index
Coronary Circulation
medicine
Humans
Radiology
Nuclear Medicine and imaging
[INFO]Computer Science [cs]
Angiology
Aged
MESH: Humans
business.industry
Research
Coronary Stenosis
Magnetic resonance imaging
medicine.disease
MESH: Adenosine
MESH: Male
MESH: Sensitivity and Specificity
MESH: Coronary Angiography
[SDV.IB.IMA] Life Sciences [q-bio]/Bioengineering/Imaging
lcsh:RC666-701
MESH: Dipyridamole
business
MESH: Female
Zdroj: Journal of Cardiovascular Magnetic Resonance
Journal of Cardiovascular Magnetic Resonance, 2010, 12 (1), pp.29. ⟨10.1186/1532-429X-12-29⟩
Journal of Cardiovascular Magnetic Resonance, BioMed Central, 2010, 12 (1), pp.29. ⟨10.1186/1532-429X-12-29⟩
Journal of Cardiovascular Magnetic Resonance, Vol 12, Iss 1, p 29 (2010)
ISSN: 1532-429X
1097-6647
DOI: 10.1186/1532-429X-12-29⟩
Popis: Aim Evaluation of the diagnostic accuracy of stress perfusion cardiovascular magnetic resonance for the diagnosis of significant obstructive coronary artery disease (CAD) through meta-analysis of the available data. Methodology Original articles in any language published before July 2009 were selected from available databases (MEDLINE, Cochrane Library and BioMedCentral) using the combined search terms of magnetic resonance, perfusion, and coronary angiography; with the exploded term coronary artery disease. Statistical analysis was only performed on studies that: (1) used a [greater than or equal to] 1.5 Tesla MR scanner; (2) employed invasive coronary angiography as the reference standard for diagnosing significant obstructive CAD, defined as a [greater than or equal to] 50% diameter stenosis; and (3) provided sufficient data to permit analysis. Results From the 263 citations identified, 55 relevant original articles were selected. Only 35 fulfilled all of the inclusion criteria, and of these 26 presented data on patient-based analysis. The overall patient-based analysis demonstrated a sensitivity of 89% (95% CI: 88-91%), and a specificity of 80% (95% CI: 78-83%). Adenosine stress perfusion CMR had better sensitivity than with dipyridamole (90% (88-92%) versus 86% (80-90%), P = 0.022), and a tendency to a better specificity (81% (78-84%) versus 77% (71-82%), P = 0.065). Conclusion Stress perfusion CMR is highly sensitive for detection of CAD but its specificity remains moderate.
Databáze: OpenAIRE
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