Isolated subtle asymmetric slowing on EEG leading to a diagnosis of autoimmune encephalitis
| Autor: | Deema Obiedat, Belal Aldabbour, Abdel-Hameed Al-Mistarehi, Mohammad G. Qasaimeh, Ahmed Yassin, Suha Aqaileh, Khalid El-Salem, Majdi Al Qawasmeh |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pediatrics
medicine.medical_specialty Neurology Electroencephalography Lateralization of brain function lcsh:RC321-571 03 medical and health sciences 0302 clinical medicine Paraneoplastic syndromes medicine 030212 general & internal medicine lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry Autoimmune encephalitis medicine.diagnostic_test business.industry General Neuroscience medicine.disease Highly sensitive Psychiatry and Mental health EEG Findings Encephalitis Surgery Neurology (clinical) Neurosurgery Pshychiatric Mental Health business 030217 neurology & neurosurgery |
| Zdroj: | The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, Vol 56, Iss 1, Pp 1-6 (2020) |
| ISSN: | 1687-8329 |
| DOI: | 10.1186/s41983-020-00180-5 |
| Popis: | Background Autoimmune encephalitis presents with subacute neurological, psychiatric, and behavioral symptoms. In many cases, MRI and CSF studies return normal. Laboratory testing for pathogenic neuronal antibodies is limited by accessibility and sensitivity issues. Finally, the different diagnostic approaches lack consensus and have until recently been largely retrospective. Collectively, these factors predispose for delays in diagnosis and treatment in many cases. Case presentation We describe the case of a 42-year-old woman who did not initially meet the newly proposed criteria for probable autoimmune encephalitis, but in whom the detection on electroencephalogram (EEG) of subtle asymmetric slowing of the left hemisphere ultimately led to the diagnosis. Discussion EEG is highly sensitive and rarely normal in encephalitis. The recently introduced diagnostic criteria for autoimmune encephalitis included new-onset seizures in the earliest steps in the algorithm but did not yet incorporate EEG findings. We encourage practicing physicians to use EEG as an early, sensitive diagnostic tool for cases suspected to have autoimmune encephalitis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink