Severe liver and renal injuries following cerebral angiography: late life-threatening complications of non-ionic contrast medium administration

Autor: Marcelo Cunio Machado Fonseca, Paulo Sérgio Lucas da Silva, Emerson Yukio Kubo
Rok vydání: 2015
Předmět:
Zdroj: Child's Nervous System. 32:733-737
ISSN: 1433-0350
0256-7040
DOI: 10.1007/s00381-015-2889-x
Popis: Contrast-induced nephropathy requiring dialysis support is rarely reported, whereas severe liver injury after contrast agent administration has not been described in children yet. A previously healthy 10-year-old boy with diagnosis of cerebral arteriovenous malformation underwent a cerebral angiogram study with iohexol (3 mL/kg). After 4 days, he developed vomiting and abdominal pain. Laboratory results showed abnormal liver function tests, including marked elevation of transaminases. In the next day, he evolved with oliguria and blood arterial hypertension. At this time, he presented with worsening renal function tests. Peritoneal dialysis was required for 13 days. The patient had a self-limiting course and received only supportive treatment. This report highlights delayed complications related to low non-ionic contrast media with a rare presentation that can be neglected or unrecognized by pediatric specialties.
Databáze: OpenAIRE