| Autor: |
Uday C. Mashelkar, Ramanatham Vinodkumar, Sanjay Dashrath Vaidya, Shekar Bhaskar Bhirud, Umesh Bhise, Bobba Venkata Siva Kumar |
| Rok vydání: |
2008 |
| Předmět: |
|
| Zdroj: |
ARKIVOC, Vol 2008, Iss 14, Pp 37-49 (2008) |
| ISSN: |
1551-7012 |
| DOI: |
10.3998/ark.5550190.0009.e05 |
| Popis: |
Synthesis of a series of novel substituted benzimidazole derivatives by the condensation of o- phenylenediamine (OPDA, 1) with 4-bromobenzoic acid (2) and subsequent reactions of the benzimidazole with different electrophilic reagents is reported. The latter compounds were reacted with styrene and tert-butyl acrylate following Heck Coupling. All the compounds synthesized were screened for their potential anti-bacterial, anti-asthmatic and anti-diabetic properties, which exibibited some promising results towards testing organism in vivo. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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