Serum complement C3 has a stronger association with insulin resistance than high sensitive C-reactive protein in non-diabetic Chinese
| Autor: | Qifu Li, Bangqiong Wang, Li Zhong, Rong Luo, Qingfeng Cheng, Hua Qing, Zhoujun Liu, Yuanjuan Jiang |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male medicine.medical_specialty Waist medicine.medical_treatment Immunology Young Adult Insulin resistance Asian People Risk Factors Internal medicine medicine Humans Aged Aged 80 and over Pharmacology biology Receiver operating characteristic Insulin C-reactive protein Complement C3 Middle Aged medicine.disease Rheumatology C-Reactive Protein Endocrinology Quartile biology.protein Female Insulin Resistance Nephelometry Biomarkers |
| Zdroj: | Inflammation Research. 60:63-68 |
| ISSN: | 1420-908X 1023-3830 |
| DOI: | 10.1007/s00011-010-0236-y |
| Popis: | To compare association of complement C3 (C3) and high sensitive C-reactive protein (hs-CRP) with insulin resistance. A total of 587 non-diabetic Chinese aged 20–80 years were recruited. Complement C3 and hs-CRP were measured by the rate nephelometry method and the particle enhanced immunoturbidimetric method, respectively, and their relationship to insulin resistance was assessed. Insulin resistance was defined as the upper quartile of HOMA2-IR. Complement C3 and hs-CRP were significantly higher in subjects with insulin resistance than those without. Complement C3 was the second strongest determinant of insulin in the study (β = 0.34, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink