Methods for the Synthesis of Substituted Azetines

Autor:	Dorian Didier, Michael Eisold, Geoffrey Haas, Andreas N. Baumann, Yu Min Kiw, Arif Music
Rok vydání:	2017
Předmět:	010405 organic chemistry Chemistry Organic Chemistry Molecule Physical and Theoretical Chemistry 010402 general chemistry 01 natural sciences Biochemistry Combinatorial chemistry 0104 chemical sciences
Zdroj:	Organic Letters. 19:5681-5684
ISSN:	1523-7052 1523-7060
DOI:	10.1021/acs.orglett.7b02847
Popis:	Spurred on by the recent emerging interest from the chemical community for unsaturated four-membered heterocycles, an unprecedented approach to nitrogen-containing four-membered rings has been designed. 3,4-Disubstituted 2-azetines were synthesized from commercially available substrates, allowing for a straightforward access to a new library of chiral functionalized azetidines and amino alcohols. This original approach was applied to efficiently prepare functionalized azobenzenes, an emerging class of molecules with a large potential in photopharmacology.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::637954715c156f2b7895b6a23f947fa1 https://doi.org/10.1021/acs.orglett.7b02847 Zobrazit plný text záznamu