Tick-Borne Encephalitis Electrochemical Detection by Multilayer Perceptron on Liquid-Metal Interface
| Autor: | Weini T. Tesfatsion, Konstantin G. Nikolaev, Kostya S. Novoselov, Artemii S. Ivanov, Alex M. Egorov, Mikhail F. Vorovitch, Stanislav O. Yurchenko, Ekaterina V. Skorb, Maya Yu. Rubtsova, Anna A. Stekolshchikova, Aydar A. Ishmukhametov, Daria V. Andreeva |
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| Rok vydání: | 2022 |
| Předmět: |
Liquid metal
Materials science business.industry Interface (computing) Biochemistry (medical) Alloy Biomedical Engineering Tick-borne encephalitis chemistry.chemical_element General Chemistry Electrochemical detection engineering.material medicine.disease Biomaterials chemistry Multilayer perceptron medicine engineering Optoelectronics Gallium business Indium |
| Zdroj: | ACS applied bio materials. 3(11) |
| ISSN: | 2576-6422 |
| Popis: | This work depicts an electrochemical hydrogel-eutectic gallium indium alloy interface for the detection of tick-borne encephalitis (TBE) virus. This interface allows recording of nonlinear current-voltage responses, depending on the composition of the hydrogel. The current-voltage data for the machine learning model are trained by a multilayer perceptron. This model accurately recognizes the TBE antibody, antigen, and an antibody-antigen complex in mixture with interfering bovine serum albumin with 93% accuracy. Thus, this interface can be used as a convenient method for expressed viruses and pathogens detection. |
| Databáze: | OpenAIRE |
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