Changes in cardiac output and incidence of volume overload in cirrhotics receiving 20% albumin infusion
| Autor: | Manoj Kumar, Jelen S Khumuckham, Saggere Muralikrishna Shasthry, Shiv Kumar Sarin |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Liver Cirrhosis Male medicine.medical_specialty Cardiac output Volume overload Cardiomyopathy Diastole Hemodynamics 03 medical and health sciences Liver disease 0302 clinical medicine Internal medicine Albumins medicine Humans Prospective Studies Cardiac Output Blood Volume Hepatology business.industry Incidence (epidemiology) Albumin Middle Aged medicine.disease Echocardiography 030220 oncology & carcinogenesis Cardiology 030211 gastroenterology & hepatology Female business Cardiomyopathies |
| Zdroj: | Liver international : official journal of the International Association for the Study of the Liver. 37(8) |
| ISSN: | 1478-3231 |
| Popis: | Introduction Cirrhotic patients are prone to develop volume over load, have increased capillary permeability and latent or overt cardiomyopathy. Whether albumin infusion causes volume overload in cirrhotics has not been adequately studied Patients and Methods Ninety nine consecutive cirrhotic patients receiving 1gm per kg albumin infusion were evaluated for development of volume overload. Clinical, echocardiographic and hemodynamic changes were closely monitored during and after albumin infusion Results Thirty (30.30%) patients developed volume overload. Patients with higher BMI (p=0.003), lower CTP (p=0.01) and MELD (p=0.034) were more often associated with the development of volume overload. Though baseline diastolic dysfunction was present in 82.8% patients, it did not influence development of volume overload or changes in the cardiac output. The cardiac output increased significantly after albumin infusion [4.9±1.554 L/min) to 5.86±1.85 L/min), p |
| Databáze: | OpenAIRE |
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