The Discovery of Insulin: An Important Milestone in the History of Medicine
| Autor: | Nicola Luigi Bragazzi, Ignazio Vecchio, Cristina Tornali, Mariano Martini |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
History Paulescu Endocrinology Diabetes and Metabolism medicine.medical_treatment history of medicine 030209 endocrinology & metabolism Review Banting and Best Diabetes Discovery of insulin History of medicine Paulescu Endocrinology Diabetes and Metabolism History of medicine lcsh:Diseases of the endocrine glands. Clinical endocrinology Banting and Best Diabetes Discovery of insulin 03 medical and health sciences Endocrinology 0302 clinical medicine Milestone (project management) medicine lcsh:RC648-665 diabetes Insulin humanities Diabetes and Metabolism Trace (semiology) 030104 developmental biology discovery of insulin Classics |
| Zdroj: | Frontiers in Endocrinology, Vol 9 (2018) Frontiers in Endocrinology |
| ISSN: | 1664-2392 |
| DOI: | 10.3389/fendo.2018.00613 |
| Popis: | The discovery of insulin represents an authentic breakthrough, characterized, at the same time, by contrasts, controversies and disputes among scholars, as well as by great disappointments, failures and hopes. It is the story of famous, almost famous and little known people, of serendipities, discoveries and re-discoveries. The discovery of insulin has been a milestone and has truly revolutionized both the therapy and the prognosis of the diabetes, one of the diseases most studied in the history of medicine, whose first mentions trace back to a collection of ancient Egyptian, Indian and Chinese textbooks. As stated by Colwell, the introduction of insulin has heralded the end of the so-called “pre-insulin era” or “frustration era”, paving the way for a new era and clinical advancements. The current review offers a broad, comprehensive overview of main steps culminating into insulin discovery, including recent advancements such as personalized and individualized insulin therapy. |
| Databáze: | OpenAIRE |
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