Association of 25-hydroxy-vitamin D levels with semen and hormonal parameters
| Autor: | C. Matthew Peterson, A. Wayne Meikle, Joseph B. Stanford, Douglas T. Carrell, Ahmad O. Hammoud, Mark Gibson |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Urology Population Semen Semen analysis Body Mass Index Sex hormone-binding globulin Sex Hormone-Binding Globulin Internal medicine medicine Vitamin D and neurology Humans Testosterone Vitamin D Spermatogenesis education Letter to the Editor Sperm motility Aged education.field_of_study Estradiol biology medicine.diagnostic_test General Medicine Luteinizing Hormone Middle Aged Sperm Semen Analysis Cross-Sectional Studies Endocrinology Sperm Motility biology.protein Population study Follicle Stimulating Hormone |
| Zdroj: | Asian Journal of Andrology |
| ISSN: | 1745-7262 1008-682X |
| Popis: | Vitamin D levels have been linked to various health outcomes including reproductive disorders. The purpose of this study was to explore the association between serum vitamin D level (25-hydroxy-vitamin D, or 25OHD) and semen and hormonal parameters. This is a cross-sectional study that included 170 healthy men recruited for the study of spermatogenesis from the general population. Men completed general and reproductive health questionnaires, and donated blood and semen samples. The main measures were hormonal (total and free testosterone, sex hormone-binding globulin, estradiol, follicle-stimulating hormone and luteinizing hormone) and semen parameters, adjusted (n=147) for age, body mass index (BMI), season, alcohol intake and smoking, in relation to categories of vitamin D levels, determined a priori. The mean age of the study population was 29.0±8.5 years and mean BMI was 24.3±3.2 kg m(-2). The mean 25OHD was 34.1±15.06 ng ml(-1). BMI showed a negative association with 25OHD. Sperm concentration, sperm progressive motility, sperm morphology, and total progressively motile sperm count were lower in men with '25OHD≥50 ng ml(-1)' when compared to men with '20 ng ml(-1)≤25OHD |
| Databáze: | OpenAIRE |
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