Change of clinical characteristics of ulcerative colitis in Japan: analysis of 844 hospital-based patients from 1981 to 2000

Autor: Junichirou Nasu, Yasushi Shiratori, Hiroshi Yamamoto, Jun Kato, Motoaki Kuriyama, Motowo Mizuno, Tsuyoshi Fujimoto, Hiroyuki Okada
Rok vydání: 2007
Předmět:
Zdroj: European Journal of Gastroenterology & Hepatology. 19:229-235
ISSN: 0954-691X
DOI: 10.1097/meg.0b013e3280110fb9
Popis: Although the number of ulcerative colitis patients has increased rapidly in Japan, few reports have been published regarding their clinical aspects. We investigated the clinical characteristics and chronological change of ulcerative colitis in Japanese patients. METHODS: Patients diagnosed with ulcerative colitis during the period from 1981 to 2000 were registered and their clinical profiles were analyzed. The chronological changes in clinical aspects, such as onset age, sex distribution, severity, extent of disease, clinical course, and corticosteroid use, were also determined. RESULTS: A total of 844 patients were registered, composed of 431 men and 413 women, with a median onset age of 34 years. The proportion of mild colitis and proctitis was significantly larger in patients with an onset at over 60 years of age, relative to those with an onset at less than 30 years (P
Databáze: OpenAIRE