Spontaneous Regression of Advanced Hepatocellular Carcinoma
| Autor: | Rupal Bandi, Thomas V. Cacciarelli, Vivek Sharma, Dhiraj J Sonbare, Obaid S. Shaikh |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Oncology
Poor prognosis medicine.medical_specialty Cirrhosis medicine.medical_treatment Liver transplantation medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Case and Review tumor thrombus Internal medicine Complete regression medicine lcsh:RC799-869 business.industry cirrhosis Gastroenterology medicine.disease Regression digestive system diseases 030220 oncology & carcinogenesis Hepatocellular carcinoma 030211 gastroenterology & hepatology lcsh:Diseases of the digestive system. Gastroenterology Steatohepatitis business Carcinogenesis carcinogenesis |
| Zdroj: | Case Reports in Gastroenterology, Vol 14, Iss 3, Pp 491-496 (2020) Case Reports in Gastroenterology |
| ISSN: | 1662-0631 |
| Popis: | Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality. The tumor carries poor prognosis with curative therapeutic options limited to surgical resection, tumor ablation, and liver transplantation. Rarely, there is spontaneous regression of the tumor. We describe the case of a 74-year-old male with cirrhosis from non-alcoholic steatohepatitis who developed advanced HCC that was associated with tumor invasion of the portal vein and marked elevation of serum alfa-fetoprotein level. The patient received no cancer-specific therapy. However, 1 year after the initial diagnosis, he was noted to have complete regression of the tumor. In this report, we discuss possible mechanisms of spontaneous tumor regression and its therapeutic implications. |
| Databáze: | OpenAIRE |
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