Autonomic and neuroendocrine responses to a psychosocial stressor in adults with autistic spectrum disorder
| Autor: | Herman van Engeland, Christine C. Gispen-de Wied, Victor M. Wiegant, Herman Westenberg, Bertine E. Lahuis, Lucres M. C. Jansen |
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| Přispěvatelé: | Pediatric surgery, Amsterdam Neuroscience - Compulsivity, Impulsivity & Attention, APH - Mental Health, Amsterdam Reproduction & Development (AR&D) |
| Jazyk: | angličtina |
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male medicine.medical_specialty Vasopressin Epinephrine Vasopressins Autonomic Nervous System Oxytocin Norepinephrine Adrenocorticotropic Hormone Internal medicine Heart rate Developmental and Educational Psychology medicine Humans Psychology Speech Autistic Disorder Stressor medicine.disease Developmental disorder Autonomic nervous system Endocrinology Autism Anxiety Female medicine.symptom Stress Psychological hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | Journal of Autism and Developmental Disorders, 36(7), 891-899. Springer New York Jansen, L M C, Gispen-De Wied, C C, Wiegant, V M, Westenberg, H G M, Lahuis, B E & Van Engeland, H 2006, ' Autonomic and neuroendocrine responses to a psychosocial stressor in adults with autistic spectrum disorder ', Journal of Autism and Developmental Disorders, vol. 36, no. 7, pp. 891-899 . https://doi.org/10.1007/s10803-006-0124-z |
| ISSN: | 0162-3257 |
| Popis: | Objective of the study was to replicate in adults our previous findings of decreased heart rate and normal endocrine responses to stress in autistic children and to elucidate the discrepancy between autonomic and endocrine stress responses by including epinephrine, norepinephrine, oxytocin and vasopressin measurements. Ten autistic spectrum disorder (ASD) adults were compared to 14 healthy controls in their response to a psychosocial stressor (public speaking). ASD patients showed decreased heart rate, but normal cortisol responses, consistent with our prior findings in children. No differences in norepinephrine, epinephrine, oxytocin or vasopressin responses to stress were found. However, in contrast to previous findings in low functioning autistic children, ASD adults showed increased basal oxytocin levels, which may be related to developmental factors. |
| Databáze: | OpenAIRE |
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