Hemophilia Growth and Development Study: Baseline Neurodevelopmental Findings
| Autor: | Brain Belden, Patricia M. Moylan, Roberta A. Olson, Anthony A. Scott, Charles F. Contant, Marilyn Schiller, Janice D. Bordeaux, Suzanne D. Hill, Katherine A. Loveland, Terece S. Bell, Valerie A. Cool, John M. Watkins, Mary Bowman, Patricia A. Sirois, James A. Stehbens |
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| Rok vydání: | 1994 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Adolescent Population Neuropsychological Tests Hemophilia A Developmental psychology Child Development Acquired immunodeficiency syndrome (AIDS) Hemophilias HIV Seropositivity Developmental and Educational Psychology medicine Humans Longitudinal Studies Prospective Studies Child Prospective cohort study education education.field_of_study Intelligence quotient Wechsler Scales Neuropsychology virus diseases Wechsler Adult Intelligence Scale medicine.disease El Niño Pediatrics Perinatology and Child Health Psychology Follow-Up Studies |
| Zdroj: | Journal of Pediatric Psychology. 19:223-239 |
| ISSN: | 1465-735X 0146-8693 |
| DOI: | 10.1093/jpepsy/19.2.223 |
| Popis: | Reported baseline findings from the neurological assessment component of the Hemophilia Growth and Development Study (HGDS). HIV-positive (HIV+; n = 207) and HIV-negative (HIV-; n = 126) young males with hemophilia ages 6 to 18 years, were enrolled in a prospective study of their growth and development. At baseline, HIV+ and HIV- subjects were not significantly different in test performance. The number of subjects exhibiting below-average performance in three or more areas assessed was about 25% overall. For both groups, mean test scores were within the average range. Academic and adaptive skills were lower than expected based on mean IQ scores, and more behavioral/emotional problems than expected were reported by parents. Absolute CD4 cell counts per mm3 were not related to neuropsychological performance at baseline. Results suggest that the subjects with HIV were relatively free of HIV-related neuropsychological impairment at baseline and that observed differences from a general population reflect effects of hemophilia as a chronic illness. |
| Databáze: | OpenAIRE |
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