Reduction of visceral fat correlates with the decrease in the number of obesity-related cardiovascular risk factors in Japanese with Abdominal Obesity (VACATION-J Study)
| Autor: | Iichiro Shimomura, Tetsuya Ohira, Rie Oka, Tohru Funahashi, Yuko Ishizaka, Minoru Okada, Tohru Nakagawa, Aki Hiuge-Shimizu, Naoya Watanabe, Tadashi Nakamura, Norihide Takaya, Minoru Yamakado, Shizu Suzuki, Toshiki Fukui, Ken Kishida, Yuji Matsuzawa, Tohru Yoshizumi, Hiroshi Fukuda |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty genetic structures Intra-Abdominal Fat Gastroenterology Body Mass Index Japan Weight loss Risk Factors Internal medicine Weight Loss Internal Medicine medicine Humans Risk factor Abdominal obesity Aged Anthropometry business.industry Biochemistry (medical) Odds ratio Middle Aged medicine.disease Obesity Endocrinology Cardiovascular Diseases Obesity Abdominal Female medicine.symptom Cardiology and Cardiovascular Medicine business Body mass index |
| Zdroj: | Journal of atherosclerosis and thrombosis. 19(11) |
| ISSN: | 1880-3873 |
| Popis: | AIM Visceral fat accumulation is associated with obesity-related cardiovascular risk factor accumulation and atherosclerosis. The present study investigated whether one-year reduction of the visceral fat area (VFA) correlates with a decrease in the number of such factors in Japanese with or without visceral fat accumulation. METHODS The study subjects comprised 5,347 Japanese, who underwent health check-ups in 2007 and 2008, including measurements of VFA and subcutaneous fat area (SFA) by computed tomography at 9 centers in Japan. Subjects with one or more such factor(s) were categorized into tertiles based on the one-year change in VFA. We investigated the multivariate age, sex, and one-year change in SFA-adjusted odds ratios (ORs) and 95% confidence intervals (CI) for reductions in the number of risk factors in each of the three categories based on the one-year change in VFA, in subjects with one or more such factors (n= 3,648). RESULTS In the entire group (n=3,648), the OR and 95%CI for reductions in the number of risk factors in the first tertile were 0.804 (0.673-0.962, p=0.0172), compared with the second tertile set at 1.0. Subjects with VFA |
| Databáze: | OpenAIRE |
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