Antigliadin Antibodies Associated with Chronic Mucocutaneous Candidiasis

Autor: Santiago Gómez Díez, Narciso Perez Oliva, Yolanda Hidalgo Garcia, Lourdes Tricas Aizpún
Rok vydání: 2002
Předmět:
Zdroj: Pediatric Dermatology. 19:415-418
ISSN: 1525-1470
0736-8046
DOI: 10.1046/j.1525-1470.2002.00117.x
Popis: Chronic mucocutaneous candidiasis (CMC) is a primary immunodeficiency disease clinically characterized by Candida infection of the skin, mucous membranes, or nails that is refractory to traditional treatment. We present a typical case of a 13-year-old boy with an onset of illness at 1 month of age in the form of oral thrush. At age 2-3 years the patient began to have external otitis caused by Candida albicans and recurrent upper respiratory tract infections. Analytical studies detected iron deficiency and circulating antigliadin antibodies. Immunologic findings excluded other possible immunodeficiencies. Significant clinical improvement was produced by therapy with orally administered fluconazole. The significance of antigliadin antibodies is discussed.
Databáze: OpenAIRE