Comparison of point-shear wave elastography (ElastPQ) and transient elastography (FibroScan) for liver fibrosis staging in patients with non-alcoholic fatty liver disease

Autor: Davide Roccarina, Laura Iogna Prat, Giada Pallini, Marta Guerrero Misas, Elena Buzzetti, Francesca Saffioti, Francesco M. Aricò, Anna Mantovani, Evangelia Koutli, Atul Goyale, Matteo Rosselli, Tu Vinh Luong, Massimo Pinzani, Emmanuel A. Tsochatzis
Rok vydání: 2022
Předmět:
Zdroj: Liver international : official journal of the International Association for the Study of the LiverREFERENCES. 42(10)
ISSN: 1478-3231
Popis: ElastPQ is a point shear wave elastography technique used to non-invasively assess liver fibrosis. We compared liver stiffness measurements (LSM) by ElastPQ and fibroscan transient elastography (F-TE) in a cohort of patients with non-alcoholic fatty liver disease (NAFLD). We further evaluated the performance of ElastPQ in a subgroup of patients with available liver histology.We included patients with NAFLD who presented in a dedicated multidisciplinary clinic. Anthropometric parameters, blood tests and elastography measurements were obtained using F-TE and ElastPQ as part of routine clinical care.We enrolled 671 patients with NAFLD, mean age 55.8 ± 13 years, body mass index (BMI) 31.5 ± 5.7 kg/mElastPQ shows an excellent correlation with F-TE in patients with NAFLD, which was better for lower LSM. The optimal cut-off values of ElastPQ are lower than those of F-TE for individual stages of fibrosis. ElastPQ has similar diagnostic accuracy to F-TE for all stages of fibrosis.
Databáze: OpenAIRE
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