Electroconducting polymers for the construction of DNA or peptide arrays on silicon chips
| Autor: | Hervé Bazin, Thierry Livache, Patrice Caillat, André Roget |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Silicon
Materials science Polymers Biomedical Engineering Biophysics chemistry.chemical_element Peptide Nanotechnology Polypyrrole chemistry.chemical_compound Electrochemistry Animals Humans Pyrroles chemistry.chemical_classification Biomolecule General Medicine Polymer DNA Chip Peptide array Microelectrode chemistry Peptides Microelectrodes Biotechnology |
| Zdroj: | Biosensorsbioelectronics. 13(6) |
| ISSN: | 0956-5663 |
| Popis: | We wish to show in this paper new developments and new applications of the pyrrole copolymerization process allowing the addressing of pyrrole-modified biomolecules on microelectrode arrays. Two main developments are described: the first one concerns the development of multiplexed silicon chips bearing 128 microelectrodes instead of 48 for the passive chips. The second one deals with new applications of this grafting process concerning not only DNA chips but peptide chips too. In this way, copolymerization of pyrrole peptides on the chip (leading to peptide chip) and their immunological detection is illustrated. This technology shows a high dimensional resolution and a real versatility. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect