Convergent Synthesis of the ent-ZA′B′C′D′-Ring System of Maitotoxin
| Autor: | Hiroyuki Koshino, Masayuki Morita, Tatsuo Saito, Mikiko Sodeoka, Tadashi Nakata |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
chemistry.chemical_classification
Maitotoxin Molecular Structure 010405 organic chemistry Stereochemistry Chemistry Oxocins Organic Chemistry Iodide Convergent synthesis Stereoisomerism 010402 general chemistry 01 natural sciences Biochemistry Coupling reaction 0104 chemical sciences chemistry.chemical_compound Marine Toxins Stereoselectivity Physical and Theoretical Chemistry |
| Zdroj: | Organic Letters. 19:3203-3206 |
| ISSN: | 1523-7052 1523-7060 |
| Popis: | Stereoselective synthesis of the ent-ZA'B'C'D'-ring system of maitotoxin has been accomplished through a convergent strategy utilizing Suzuki-Miyaura cross coupling reaction of ZA'-ring alkylborane and C'D'-ring (Z)-vinyl iodide, and subsequent construction of the B'-ring by reduction of the O,S-acetal. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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