Surgical complications related to transplanted pancreas after simultaneous pancreas and kidney transplantation
| Autor: | Jacek Szmidt, Leszek Pączek, Zbigniew Gałązka, Sławomir Nazarewski, S. Frunze, Tomasz Jakimowicz, Tadeusz Grochowiecki, Magdalena Durlik, K. Madej |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Young Adult Pancreatectomy Postoperative Complications medicine Humans Pancreas Kidney transplantation Transplantation Kidney business.industry Mortality rate Graft Survival Thrombosis Middle Aged medicine.disease Kidney Transplantation Abscess Surgery surgical procedures operative medicine.anatomical_structure Pancreatitis Female Pancreas Transplantation Complication business Pancreatic abscess |
| Zdroj: | Transplantation proceedings. 46(8) |
| ISSN: | 1873-2623 |
| Popis: | Objective Simultaneous pancreas and kidney transplantation (SPTKx) is characterized by the high rate and variability of postoperative complications, which could be a limitation of this treatment. The aim of this study was to evaluate prevalence, types, and severity of postoperative complications due to pancreas graft among the simultaneous pancreas and kidney recipients. Methods Postoperative complications related to transplanted pancreas among 112 SPTKx recipients were analyzed. The cumulative survival rates for pancreas graft function and cumulative freedom from complication on day 60 after transplantation were assessed. Severity of complications was classified according to a modified Clavien-Dindo scale. Results The 12-month cumulative survival rate for pancreatic graft was 0.74. Cumulative freedom from complication on the 60th day after transplantation was 0.57. The rates for II, IIIA, IIIB, IVA, and IVB severity grades were 10,6%, 4,5%, 19,7%, 44%, and 21,2%, respectively. The most severe (IVB) transplanted pancreas complications were due to graft inflammation, infection, pancreatic abscess, and local or diffuse necrosis. The most frequent reason for graft pancreatectomy was vascular thrombosis 35.9% (14/39). The mortality rate after graft pancreatectomy was significantly lower for vascular thrombosis than for infection (0/14 vs 11/25; P Conclusion Reducing vascular thrombosis could preserve graft function rate. Preventing graft inflammation and infection would reduce mortality. |
| Databáze: | OpenAIRE |
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