The accuracy and sensitivity of diffusion-weighted magnetic resonance imaging with Apparent Diffusion Coefficients in diagnosis of recurrent cholesteatoma
| Autor: | Moustafa Talaat Abdel Hakim Ali, Ahmed Abdel Rahman, Nasr Mohamed M. Osman |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
lcsh:Medical physics. Medical radiology. Nuclear medicine
medicine.medical_specialty lcsh:R895-920 Article 030218 nuclear medicine & medical imaging Multidetector computed tomography 03 medical and health sciences 0302 clinical medicine medicine Effective diffusion coefficient Radiology Nuclear Medicine and imaging Recurrent cholesteatoma medicine.diagnostic_test business.industry Cut off value Cholesteatoma Magnetic resonance imaging Magnetic Resonance Diffusion weighted imaging medicine.disease Diffusion-Weighted Magnetic Resonance Imaging medicine.anatomical_structure Apparent diffusion coefficient Middle ear Radiology business 030217 neurology & neurosurgery |
| Zdroj: | European Journal of Radiology Open European Journal of Radiology Open, Vol 4, Iss, Pp 27-39 (2017) |
| ISSN: | 2352-0477 |
| DOI: | 10.1016/j.ejro.2017.03.001 |
| Popis: | Objective: To evaluate the accuracy and sensitivity of diffusion-weighted magnetic resonance imaging with ADC value combined with MDCT in evaluating recurrent cholesteatoma. Patients: Thirty patients (20 females and 10 males), their age ranged from 10 to 40years, had undergone a tympanomastoid surgery for a cholesteatoma of the middle ear underwent MDCT and MR DWI examination before second- or third-look surgery from May 2015 to October 2016. Results: CT showed partial opacification of the tympanomastoid cavity in 10 ears and complete opacification in 21 ears. CT detects 10 cases out of 20 cases of recurrent cholesteatoma with sensitivity 47.6%, specificity 100%, and NPP 47.6%. DWI depicted 21 out of 20 cases proved cholesteatoma patients (sensitivity 100%, specificity 90%, PPV 95.2% and P value is 0.001). All MRI of patients without cholesteatoma were correctly interpreted as showing negative findings for cholesteatoma (specificity = 100%). The ADC of cholesteatoma group (21 ears) were ranged from 553 to 759 Ã 10â3 mm2/s and the ADCs of non cholesteatoma group (10 ears) was ranged from 1495.8 to 1766.8 Ã 10â3 mm2/s. Cut off value of cholesteatoma is â¤759 Ã 10â3 mm2/s. Conclusion: MR DWI with ADC combined with MDCT has high sensitivity, specificity, accuracy in detecting recurrent cholesteatoma. Keywords: Recurrent cholesteatoma, Magnetic Resonance Diffusion weighted imaging, Apparent diffusion coefficient, Multidetector computed tomography |
| Databáze: | OpenAIRE |
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