NEURAL CORRELATES OF PHYSICAL AND MENTAL FATIGABILITY IN OLDER ADULTS

Autor: A L Rosso, E Wasson, A J Santanasto, C Rosano, M Butters, J Rejeski, H Aizenstein, N W Glynn
Rok vydání: 2018
Předmět:
Zdroj: Innovation in Aging. 2:199-200
ISSN: 2399-5300
DOI: 10.1093/geroni/igy023.733
Popis: This work examines associations of brain grey matter volumes (GMV) with physical and mental fatigability in older adults from a subsample (n=29; age=77.2 ± 5.5; 86% female) of LIFE Study participants. GMV for a priori identified brain regions were normalized to intracranial volume. Physical and mental fatigability were measured using the Pittsburgh Fatigability Scale and higher (HF) or lower (LF) fatigability were defined using established cut-points (Range: 0–50; HF physical:≥15 (65.5%); HF mental:≥13 (65.5%). We used an exploratory alpha level of p
Databáze: OpenAIRE